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Sterols

Sterols are steroid alcohols such as cholesterol, here listed with oxysterols and bile acids. They share a four-ring steroid nucleus with a hydroxyl group at carbon 3 and help to order the lipids of cell membranes. Oxysterols are oxidized cholesterol derivatives formed by enzymes or by autoxidation. 7α-Hydroxycholesterol, the product of cholesterol 7α-hydroxylase, is the first intermediate of the classic bile acid pathway. Coprostanone is an intermediate in the bacterial reduction of cholesterol to coprostanol in the gut. 24-Methylenecholesterol is a precursor in plant sterol biosynthesis and occurs in pollen. Bile acids, the end products of hepatic cholesterol breakdown, include 3β-Ursodeoxycholic acid and 7-keto-Deoxycholic acid. 16-Dehydropregnenolone acetate is a pregnane steroid used as an intermediate in steroid synthesis.

3 Items

  • 16-Dehydropregnenolone acetate
    Cat. No.
    A69139
    CAS No.
    979-02-2

    16-Dehydropregnenolone acetate

    Synonyms: 16-DPA

    16-Dehydropregnenolone acetate is a sterol compound that primarily acts as a 17α-hydroxylase and 5α-reductase inhibitor. This reagent demonstrates significant hypolipidemic and anticancer properties, making it a valuable candidate in research concerning lipid metabolism and cancer therapeutics. Additionally, 16-Dehydropregnenolone acetate serves as a drug intermediate for the synthesis of Dexamethasone and other steroidal pharmacophores, facilitating further studies in steroid biochemistry.

    In stock View Details
    100 mg
    $30.00
    250 mg
    $50.00
    All 3 sizes
  • Thiocholesterol
    Cat. No.
    A73509
    CAS No.
    1249-81-6

    Thiocholesterol

    Thiocholesterol functions as a cationic lipid and acts as a stabilizer for silver nanoparticles (SNPs). Its unique properties make it a valuable tool for research into plasma membrane dynamics and exploring drug delivery systems. Thiocholesterol’s involvement in cholesteric liquid crystals further supports its versatility in biological applications.

    In stock View Details
    25 mg
    $150.00
    50 mg
    $280.00
    All 4 sizes
  • Lipid-lowering agent-1
    Cat. No.
    A75859
    CAS No.
    2304859-34-3

    Lipid-lowering agent-1

    Lipid-lowering agent-1 is a potent inhibitor of low-density lipoprotein cholesterol (LDLC) and enhances the production of high-density lipoprotein cholesterol (HDLC). This reagent exhibits significant hypolipidemic effects, as demonstrated in preclinical studies with high-fat diet rats. It is primarily used in research focused on lipid metabolism and cardiovascular disease, offering valuable insights into potential therapeutic approaches for dyslipidemia.

    In stock View Details
    25 mg
    $1,275.00
    50 mg
    $1,625.00
    All 3 sizes

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