Litoxetine is a selective 5-HT uptake inhibitor that functions primarily through its action on serotonin transporters. It also acts as a 5-HT3 receptor antagonist, exhibiting a Ki value of 85 nM for cerebral 5-HT3 receptors. This compound is utilized in research related to depression and nausea, showcasing its potential as an antidepressant and antiemetic agent.
Litoxetine is a selective 5-HT uptake inhibitor that functions primarily through its action on serotonin transporters. It also acts as a 5-HT3 receptor antagonist, exhibiting a Ki value of 85 nM for cerebral 5-HT3 receptors. This compound is utilized in research related to depression and nausea, showcasing its potential as an antidepressant and antiemetic agent.
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