LOC14

Catalog No.: A20491
PDI inhibitor
LOC14 is a potent Protein disulfide isomerase (PDI) inhibitor with EC50 and Kd values of 500 nM and 62 nM, respectively.
Grouped product items
Product Name Price Stock Qty
LOC14 5mg
$45.00
In stock
LOC14 10mg
$78.00
In stock
LOC14 50mg
$230.00
In stock
LOC14 100mg
$460.00
In stock
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Biological Activity
Discription LOC14 is a potent Protein disulfide isomerase (PDI) inhibitor with EC50 and Kd values of 500 nM and 62 nM, respectively.
Product Information
Catalog Num A20491
Formula C16H19N3O2S
Molecular Weight 317.41
CAS Number 877963-94-5
SMILES O=C(C(C=CC=C1)=C1S2)N2CN3CCN(C(C4CC4)=O)CC3
Synonyms LOC 14, LOC-14
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 45 mg/mL (141.77 mM)
Water <1 mg/mL
Ethanol 17 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 31.5 mL 157.52 mL 315.05 mL
0.5 mM 6.3 mL 31.5 mL 63.01 mL
1 mM 3.15 mL 15.75 mL 31.5 mL
5 mM 0.63 mL 3.15 mL 6.3 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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