Lofexidine hydrochloride

Catalog No.: A58172
Adrenergic Receptor Agonist
Lofexidine hydrochloride is a selective α2-adrenergic receptor agonist, primarily utilized to mitigate the physical symptoms associated with opioid withdrawal, including heroin dependence. Its mechanism involves reducing norepinephrine release, thereby diminishing withdrawal-related discomfort. This compound is valuable in research focusing on addiction treatment and the physiological responses to opioid cessation.
Grouped product items
Size Price Stock Qty
50mg
$30.00
In stock
100mg
$45.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
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Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
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Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionLofexidine hydrochloride is a selective α2-adrenergic receptor agonist, primarily utilized to mitigate the physical symptoms associated with opioid withdrawal, including heroin dependence. Its mechanism involves reducing norepinephrine release, thereby diminishing withdrawal-related discomfort. This compound is valuable in research focusing on addiction treatment and the physiological responses to opioid cessation.
Product Information
Catalog NumA58172
FormulaC11H13Cl3N2O
Molecular Weight295.59
CAS Number21498-08-8
SMILESCC(C1=NCCN1)OC2=C(Cl)C=CC=C2Cl.[H]Cl
SynonymsBaq-168; MDL-14042
Useful Calculator

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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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