Lomeguatrib

Catalog No.: A12785

MGMT inhibitor

Lomeguatrib

Lomeguatrib Chemical Structure

CAS NO. 192441-08-0

Lomeguatrib is a potent inhibitor of O6-alkylguanine-DNA-alkyltransferase.

Availability: In stock

Package Price Qty
10 mg

Regular Price: $45.00

Special Price $36.00

25 mg

Regular Price: $90.00

Special Price $72.00

50 mg

Regular Price: $180.00

Special Price $144.00

10mM * 1mL in DMSO

Regular Price: $98.00

Special Price $78.40

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Biological Activity

Lomeguatrib is a potent inhibitor of O6-alkylguanine-DNA-alkyltransferase.
Targets
O6-alkylguanine-DNA-alkyltransferas
5 nM
In vitro DMSO 60 mg/mL (183.95 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 30.66 mL 153.29 mL 306.59 mL
0.5 mM 6.13 mL 30.66 mL 61.32 mL
1 mM 3.07 mL 15.33 mL 30.66 mL
5 mM 0.61 mL 3.07 mL 6.13 mL

*The above data is based on the productmolecular weight 326.17. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12785
Actions Inhibitor
CAS No. 192441-08-0
Formula C10H8BrN5OS
M. Wt 326.17
Purity >98%
Synonyms O6-(4-bromothenyl)guanine
SMILES C1=C(SC=C1Br)COC2=NC(=NC3=C2NC=N3)N
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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