Fig. 1 · Structure
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Lonapalene
Cat. No.
A76428
CAS
91431-42-4
Lipoxygenase Inhibitor
Lonapalene is a selective inhibitor of 5-lipoxygenase (5-LO). It exhibits significant anti-inflammatory activity by blocking the production of leukotrienes, which are mediators involved in various inflammatory conditions. This compound is primarily utilized in research aimed at understanding and exploring therapeutic interventions for diseases associated with leukotriene signaling.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 91431-42-4 |
| Applications | Lipoxygenase Inhibitor |
| Formula | C16H15ClO6 |
| Molecular Weight | 338.74 |
| Synonyms | RS4317 |
| SMILES | COC1=C(OC)C(OC(C)=O)=C2C=CC(Cl)=CC2=C1OC(C)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.