Lonaprisan

Catalog No.: A14130

progesterone receptor antagonist

Lonaprisan

Lonaprisan Chemical Structure

CAS NO. 211254-73-8

Lonaprisan is an orally bioavailable pentafluoroethyl derivative of a mifepristone-related steroid with antiprogestagenic activity.

Availability: In stock

Package Price Qty
5 mg
$220.00
10 mg
$400.00
25 mg
$800.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Hirad A. Feridooni, .et al. Acute exposure to progesterone attenuates cardiac contraction by modifying myofilament calcium sensitivity in the female mouse heart, Am J Physiol Heart Circ Physiol, 2017, Jan 1; 312(1): H46-H59 PMID: 27793852

Biological Activity

Lonaprisan is an orally bioavailable pentafluoroethyl derivative of a mifepristone-related steroid with antiprogestagenic activity.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.66 mL 98.32 mL 196.65 mL
0.5 mM 3.93 mL 19.66 mL 39.33 mL
1 mM 1.97 mL 9.83 mL 19.66 mL
5 mM 0.39 mL 1.97 mL 3.93 mL

*The above data is based on the productmolecular weight 508.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14130
Actions Antagonist
CAS No. 211254-73-8
Formula C28H29F5O3
M. Wt 508.52
Purity >98%
Synonyms ZK230211,ZK-230211,ZK 230211
SMILES CC(=O)C1=CC=C(C=C1)C2CC3(C(CCC3(C(C(F)(F)F)(F)F)O)C4C2=C5CCC(=O)C=C5CC4)C
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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