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progesterone receptor antagonist

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Catalog No. A14130

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Lonaprisan 5mg A14130-5
Lonaprisan 10mg A14130-10
Lonaprisan 25mg A14130-25

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Lonaprisan is an orally bioavailable pentafluoroethyl derivative of a mifepristone-related steroid with antiprogestagenic activity.


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Publications citing Adooq Products
Lonaprisan Citations (1)
  • Hirad A. Feridooni,et al. Acute exposure to progesterone attenuates cardiac contraction by modifying myofilament calcium sensitivity in the female mouse heart, Am J Physiol Heart Circ Physiol, 2017, Jan 1; 312(1): H46-H59 27793852

Chemical Information

Catalog Num A14130
Actions Antagonist
M. Wt 508.52
Formula C28H29F5O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 211254-73-8
Synonyms ZK230211,ZK-230211,ZK 230211
SMILES code CC(=O)C1=CC=C(C=C1)C2CC3(C(CCC3(C(C(F)(F)F)(F)F)O)C4C2=C5CCC(=O)C=C5CC4)C
Chemical Name (8S,11R,13S,14S,17S)-11-(4-acetylphenyl)-17-hydroxy-13-methyl-17-(perfluoroethyl)-6,7,8,11,12,13,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3(2H)-one

Biological Activity

Lonaprisan is an orally bioavailable pentafluoroethyl derivative of a mifepristone-related steroid with antiprogestagenic activity.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.66 mL 98.32 mL 196.65mL
0.5 mM 3.93 mL 19.66 mL 39.33 mL
1 mM 1.97 mL 9.83 mL 19.66 mL
5 mM 0.39 mL 1.97 mL 3.93 mL

*The above data is based on the productmolecular weight 508.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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