Lophophine hydrochloride is an endogenous metabolite derived from the plant Lophophora diffusa, serving as an important intermediate in the synthesis of anhalonine and lophophorine. This compound exhibits notable biological activity, with anhalonine inducing mild sedative effects in amphibian models, while lophophorine is associated with significant neuroactive responses, including prolonged convulsions, increased reflex excitability, muscle rigidity, and paralysis in both rabbit and frog models. Lophophine hydrochloride is relevant for research in neuropharmacology and the study of natural product-derived compounds.
Lophophine hydrochloride is an endogenous metabolite derived from the plant Lophophora diffusa, serving as an important intermediate in the synthesis of anhalonine and lophophorine. This compound exhibits notable biological activity, with anhalonine inducing mild sedative effects in amphibian models, while lophophorine is associated with significant neuroactive responses, including prolonged convulsions, increased reflex excitability, muscle rigidity, and paralysis in both rabbit and frog models. Lophophine hydrochloride is relevant for research in neuropharmacology and the study of natural product-derived compounds.
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