Losartan-d2 is a deuterated form of Losartan, an angiotensin II receptor antagonist. It competitively inhibits the binding of angiotensin II to the AT1 receptor with an IC50 value of 20 nM. This stable isotope is useful for research applications in pharmacokinetics, drug metabolism studies, and receptor binding assays, facilitating the investigation of Losartan's biological activity in various experimental contexts.
Losartan-d2 is a deuterated form of Losartan, an angiotensin II receptor antagonist. It competitively inhibits the binding of angiotensin II to the AT1 receptor with an IC50 value of 20 nM. This stable isotope is useful for research applications in pharmacokinetics, drug metabolism studies, and receptor binding assays, facilitating the investigation of Losartan's biological activity in various experimental contexts.
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