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LP117

Catalog No.: A76509
Lipoxygenase Inhibitor
LP117 is a potent inhibitor of 5-Lipoxygenase (5-LO), demonstrating an IC50 value of 1.1 μM. This compound impedes the synthesis of 5-LO products, thereby regulating inflammatory pathways. LP117 is applicable in research focused on inflammatory diseases, asthma, and other conditions influenced by leukotriene metabolism. Its selectivity and efficacy make it a valuable tool for studying lipoxygenase-related mechanisms in biological systems.
LP117 1056468-55-3 Lipoxygenase Inhibitor
Grouped product items
Size Price Stock Qty
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionLP117 is a potent inhibitor of 5-Lipoxygenase (5-LO), demonstrating an IC50 value of 1.1 μM. This compound impedes the synthesis of 5-LO products, thereby regulating inflammatory pathways. LP117 is applicable in research focused on inflammatory diseases, asthma, and other conditions influenced by leukotriene metabolism. Its selectivity and efficacy make it a valuable tool for studying lipoxygenase-related mechanisms in biological systems.
Product Information
Catalog NumA76509
FormulaC21H23ClN4O2S
Molecular Weight430.95
CAS Number1056468-55-3
SMILESCCCCC(SC1=NC(NC2=CC=C3N=CC=CC3=C2)=CC(Cl)=N1)C(OCC)=O
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Metabolism > Lipoxygenase