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Form	MW
LSD1-IN-49 hydrochloride This page	418.96
LSD1-IN-49	382.50

LSD1-IN-49 hydrochloride

LSD1/KDM1A Inhibitor

LSD1-IN-49 hydrochloride is an irreversible inhibitor of LSD1/KDM1A, demonstrating an IC50 of 29 nM against human LSD1. This compound functions by forming a stable adduct with flavin adenine dinucleotide (FAD) within the binding pocket of the enzyme, effectively inhibiting its enzymatic activity. LSD1-IN-49 hydrochloride is particularly valuable for research involving neurological disorders, including schizophrenia, autism spectrum disorder, and Huntington's disease.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	1422534-06-2
Applications	LSD1/KDM1A Inhibitor
Formula	C₂₆H₂₇ClN₂O
Molecular Weight	418.96
SMILES	O=C(C1=CC=C(C2=CC=CC=C2)C=C1)NC(C=C3)=CC=C3[C@H](C4)[C@@H]4NCC5CC5.Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.