Fig. 1 · Structure
Documents & Downloads
Lu 26-046
M1/M2 Receptor Agonist
Lu 26-046 is a selective agonist for the muscarinic M1 and M2 receptors, with reported affinities (Ki values) of 0.51 nM and 26 nM, respectively, while exhibiting weak antagonistic activity at the M3 receptor (Ki 5 nM). This compound demonstrates a specific stimulating effect that has been recognized in behavioral assays with rats. Lu 26-046 serves as a valuable tool in research investigating cholinergic signaling pathways and receptor subtype functions.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 143756-51-8 |
| Applications | M1/M2 Receptor Agonist |
| Formula | C10H12N2OS |
| Molecular Weight | 208.28 |
| SMILES | C#CCOC1=NSC2=C1CNC[C@H]2C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.