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Lucanthone N-oxide

DNA/RNA Synthesi Inhibitor

Lucanthone N-oxide is a potent inhibitor of Apurinic endonuclease-1 (APE-1), targeting DNA and RNA synthesis pathways. This compound exhibits significant biological activity by interfering with the function of APE-1, crucial for DNA repair and cellular survival. Lucanthone N-oxide is valuable for research applications focused on understanding DNA damage responses and developing therapeutic strategies for diseases associated with APE-1 dysregulation.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	5615-06-5
Applications	DNA/RNA Synthesi Inhibitor
Formula	C₂₀H₂₄N₂O₂S
Molecular Weight	356.48
SMILES	O=C1C2=C(SC3=C1C=CC=C3)C(C)=CC=C2NCC[N+](CC)([O-])CC

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.