Fig. 1 · Structure

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Luteolin 7-O-glucuronide

MMP Inhibitor

Luteolin 7-O-glucuronide is a potent inhibitor of Matrix Metalloproteinases (MMPs), demonstrating IC50 values of 17.63 μM for MMP-1, 7.99 μM for MMP-3, 11.42 μM for MMP-8, 12.85 μM for MMP-9, and 0.03 μM for MMP-13. This compound is valuable for research investigating the regulation of MMP activity, which plays a critical role in extracellular matrix remodeling and various pathological conditions. It is suitable for applications in studies related to cancer metastasis, tissue repair, and inflammatory disorders.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 29741-10-4
Applications MMP Inhibitor
Formula C21H18O12
Molecular Weight 462.36
Synonyms Luteolin 7-glucuronide
SMILES
O[C@H]([C@H]([C@@H]([C@@H](C(O)=O)O1)O)O)[C@@H]1OC2=CC(O)=C3C(C=C(C4=CC=C(O)C(O)=C4)OC3=C2)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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