Fig. 1 · Structure

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LXQ-217

SHP2 Inhibitor

LXQ-217 is a selective inhibitor of the SHP2 enzyme, exhibiting an IC50 of 2.01 μM. This compound effectively induces apoptosis and inhibits cellular proliferation in both in vivo and in vitro models. It serves as a valuable tool for research on SHP2-related pathways in cancer and other diseases.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2524718-79-2
Applications SHP2 Inhibitor
Formula C24H20Br2N2O5
Molecular Weight 576.23
SMILES
CCOC(C=C1)=CC=C1OC2=CC=C(C3=NN(C=O)C(C4=C(Br)C(Br)=C(O)C(O)=C4)C3)C=C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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