Fig. 1 · Structure
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LY-426965 hydrochloride
5-HT Receptor Antagonist
LY-426965 hydrochloride is a selective antagonist of the serotonin 1A receptor. This arylpiperazine compound exhibits potent antagonistic properties, distinguishing itself with no partial agonist activity. Preclinical studies indicate its potential application in addressing disorders linked to serotonin dysregulation, including smoking cessation and depression-related conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 326821-27-6 |
| Applications | 5-HT Receptor Antagonist |
| Formula | C28H39ClN2O2 |
| Molecular Weight | 471.07 |
| SMILES | O=C([C@@](C)(CCN1CCN(CC1)C2=CC=CC=C2OC)C3=CC=CC=C3)C4CCCCC4.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.