Fig. 1 · Structure
Documents & Downloads
LY-426965
5-HT Receptor Antagonist
LY-426965 is a selective antagonist of the serotonin 1A receptor, demonstrating full antagonistic activity without partial agonist effects. This arylpiperazine compound has shown potential in preclinical studies for pharmacological applications related to serotonin dysregulation, including therapeutic strategies for smoking cessation and depression-related disorders. Its specificity and potency make it a valuable tool for research in neuropharmacology and behavioral studies.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 228418-82-4 |
| Applications | 5-HT Receptor Antagonist |
| Formula | C28H38N2O2 |
| Molecular Weight | 434.61 |
| SMILES | O=C([C@@](C)(CCN1CCN(CC1)C2=CC=CC=C2OC)C3=CC=CC=C3)C4CCCCC4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.