LY-426965

Catalog No.: A29864
5-HT Receptor Antagonist
LY-426965 is a selective antagonist of the serotonin 1A receptor, demonstrating full antagonistic activity without partial agonist effects. This arylpiperazine compound has shown potential in preclinical studies for pharmacological applications related to serotonin dysregulation, including therapeutic strategies for smoking cessation and depression-related disorders. Its specificity and potency make it a valuable tool for research in neuropharmacology and behavioral studies.
Grouped product items
Size Price Stock Qty
25mg
$1,780.00
In stock
50mg
$2,280.00
In stock
100mg
$2,960.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionLY-426965 is a selective antagonist of the serotonin 1A receptor, demonstrating full antagonistic activity without partial agonist effects. This arylpiperazine compound has shown potential in preclinical studies for pharmacological applications related to serotonin dysregulation, including therapeutic strategies for smoking cessation and depression-related disorders. Its specificity and potency make it a valuable tool for research in neuropharmacology and behavioral studies.
Product Information
Catalog NumA29864
FormulaC28H38N2O2
Molecular Weight434.61
CAS Number228418-82-4
SMILESO=C([C@@](C)(CCN1CCN(CC1)C2=CC=CC=C2OC)C3=CC=CC=C3)C4CCCCC4
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