Catalog No.: A11017
TGF-βR Inhibitor
LY2157299 is an orally active transforming growth factor beta receptor (TGF-βR) kinase inhibitor.
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LY2157299 5mg
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LY2157299 10mg
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LY2157299 25mg
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LY2157299 100mg
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LY2157299 10mM * 1mL in DMSO
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Adooq Products cited in reputable paper
Adooq's LY2157299 has been cited by 4 publications
  • Yuri Nagaoka, .et al. , Arch Biochem Biophys, 2024, Jan:751:109824 PMID: 37984759
  • Eunji Jang, .et al. , Exp Mol Med, 2023, May;55(5):974-986 PMID: 37121972
  • Satoshi Endo, .et al. , Nutr Res, 2019, 4 November
  • Oguri G, .et al. , Am J Physiol Heart Circ Physiol., 2014, 307(9):H1339-52 PMID: 25172898
  • Biological Activity
    Discription LY2157299 is an orally active transforming growth factor beta receptor (TGF-βR) kinase inhibitor.
    Target Value
    Product Information
    Catalog Num A11017
    Formula C22H19N5O
    Molecular Weight 369.4
    CAS Number 700874-72-2
    Synonyms LY-2157299

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    In vitro (25°C) DMSO 66 mg/mL (178.65 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 1%CMC-Na 28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 27.07 mL 135.35 mL 270.71 mL
    0.5 mM 5.41 mL 27.07 mL 54.14 mL
    1 mM 2.71 mL 13.54 mL 27.07 mL
    5 mM 0.54 mL 2.71 mL 5.41 mL
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    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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