LY2157299

Name: LY2157299
SKU: A11017
Price: 45 USD
Rating: 5 (4 reviews)

Catalog No.: A11017

TGF-βR Inhibitor

Adooq's LY2157299 has been cited by 4 publications

LY2157299 is an orally active transforming growth factor beta receptor (TGF-βR) kinase inhibitor.

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Grouped product items
Product Name	Price	Stock
LY2157299 5mg	$45.00	In stock
LY2157299 10mg	$65.00	In stock
LY2157299 25mg	$140.00	In stock
LY2157299 100mg	$260.00	In stock
*LY2157299 10mM 1mL in DMSO**	$70.00	In stock
Bulk Size	Bulk Discount

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Important Notice: For research use only. We do not sell to patients.

Data Sheet

SDS

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Adooq Products cited in reputable paper

Adooq's LY2157299 has been cited by 4 publications

Yuri Nagaoka, .et al. , Arch Biochem Biophys, 2024, Jan:751:109824 PMID: 37984759

Eunji Jang, .et al. , Exp Mol Med, 2023, May;55(5):974-986 PMID: 37121972

Satoshi Endo, .et al. , Nutr Res, 2019, 4 November

Oguri G, .et al. , Am J Physiol Heart Circ Physiol., 2014, 307(9):H1339-52 PMID: 25172898

Biological Activity

Discription

LY2157299 is an orally active transforming growth factor beta receptor (TGF-βR) kinase inhibitor.

Targets

Target	Value

Product Information

Catalog Num	A11017
Formula	C22H19N5O
Molecular Weight	369.4
CAS Number	700874-72-2
SMILES	CC1=CC=CC(=N1)C2=NN3CCCC3=C2C4=C5C=C(C=CC5=NC=C4)C(=O)N
Synonyms	LY-2157299
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility

In vitro (25°C)	DMSO	66 mg/mL (178.65 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	1%CMC-Na	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	27.07 mL	135.35 mL	270.71 mL
0.5 mM	5.41 mL	27.07 mL	54.14 mL
1 mM	2.71 mL	13.54 mL	27.07 mL
5 mM	0.54 mL	2.71 mL	5.41 mL

Useful Calculator

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This equation is commonly abbreviated as: C₁V₁ = C₂V₂