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Fig. 1 · Structure
Cat. No.
A50809
CAS No.
132392-39-3
Formula
C20H30N2O2S
Mol. Weight
362.53

Documents & Downloads

LY221068

Cat. No. A50809 CAS 132392-39-3

Anti-oxidant, Lipid Peroxidation/5-lipoxygenase Inhibitor

LY221068 is a potent inhibitor of iron-dependent lipid peroxidation and 5-lipoxygenase, exhibiting notable antioxidant properties. This compound demonstrates significant anti-inflammatory activity, particularly in preclinical models of arthritis, such as the Freund's Complete Adjuvant-induced arthritis model in rats, where it effectively reduces bone damage and paw swelling. LY221068 serves as a valuable tool for investigating inflammatory processes and potential therapeutic approaches in arthritis research.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 132392-39-3
Applications Anti-oxidant, Lipid Peroxidation/5-lipoxygenase Inhibitor
Formula C20H30N2O2S
Molecular Weight 362.53
SMILES
O=C1N(CS/C1=C\C2=CC(C(C)(C)C)=C(C(C(C)(C)C)=C2)O)N(C)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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