Fig. 1 · Structure

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LY3027788 hydrochloride

Prodrug of LY3020371

LY3027788 hydrochloride is a prodrug of LY3020371, acting as a selective antagonist of the mGlu2/3 receptors. This compound demonstrates significant antidepressant activity, making it a valuable tool in research focused on mood disorders. LY3027788 hydrochloride is primarily utilized to explore mechanisms underlying glutamate receptor modulation and its implications in therapeutic contexts for neuropsychiatric conditions.

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Specifications

Manufacturer Adooq Bioscience
Actions Antagonist
CAS Number 1377615-55-8
Applications Prodrug of LY3020371
Formula C25H32ClF2NO11S
Molecular Weight 628.04
SMILES
O=C([C@@]1(N)[C@]2([H])[C@@H](C(OCOC(OC(C)C)=O)=O)[C@]2([H])[C@H](O)[C@H]1CSC3=CC=C(F)C(F)=C3)OCOC(OC(C)C)=O.[H]Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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