Fig. 1 · Structure
Documents & Downloads
LY3027788
Prodrug of LY3020371
LY3027788 is a prodrug of LY3020371, functioning as a selective antagonist of the mGlu2/3 receptors. This compound exhibits potent oral bioavailability and has demonstrated antidepressant efficacy in preclinical studies. It is relevant for research focused on mood disorders and the exploration of glutamatergic signaling pathways in neuropharmacology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 1377615-76-3 |
| Applications | Prodrug of LY3020371 |
| Formula | C25H31F2NO11S |
| Molecular Weight | 591.58 |
| SMILES | O=C([C@@]1(N)[C@]2([H])[C@@H](C(OCOC(OC(C)C)=O)=O)[C@]2([H])[C@H](O)[C@H]1CSC3=CC=C(F)C(F)=C3)OCOC(OC(C)C)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.