LY3526318 is a selective antagonist of the TRPA1 ion channel, with an IC50 of 5-6 μM. This compound effectively inhibits TRPA1-mediated pain signal transduction, demonstrating notable analgesic activity. LY3526318 is primarily utilized in research focused on chronic pain conditions, including diabetic peripheral neuropathy, chronic low back pain, and osteoarthritis-related pain.
LY3526318 is a selective antagonist of the TRPA1 ion channel, with an IC50 of 5-6 μM. This compound effectively inhibits TRPA1-mediated pain signal transduction, demonstrating notable analgesic activity. LY3526318 is primarily utilized in research focused on chronic pain conditions, including diabetic peripheral neuropathy, chronic low back pain, and osteoarthritis-related pain.
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