LY367385 hydrochloride is a selective antagonist of the metabotropic glutamate receptor 1a (mGluR1a). It exhibits a potent inhibitory effect on quisqualate-induced phosphoinositide hydrolysis, with an IC50 value of 8.8 μM. This compound has demonstrated neuroprotective properties and exhibits anticonvulsant and antiepileptic effects, making it valuable for research in neurological disorders and related pharmacological studies.
LY367385 hydrochloride is a selective antagonist of the metabotropic glutamate receptor 1a (mGluR1a). It exhibits a potent inhibitory effect on quisqualate-induced phosphoinositide hydrolysis, with an IC50 value of 8.8 μM. This compound has demonstrated neuroprotective properties and exhibits anticonvulsant and antiepileptic effects, making it valuable for research in neurological disorders and related pharmacological studies.
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