LY393558

Catalog No.: A46017
5-HT Transporter Inhibitor
LY393558 is a potent, orally active inhibitor of the serotonin transporter (5-HT transporter) and an antagonist of the 5-HT1B and 5-HT1D receptors. This compound significantly increases extracellular serotonin levels in the frontal cortex of mouse models. LY393558 is valuable for research focused on depression and related serotonin modulation studies.
Grouped product items
Size Price Stock Qty
1mg
$60.00
In stock
5mg
$265.00
In stock
10mg
$485.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
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Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
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Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionLY393558 is a potent, orally active inhibitor of the serotonin transporter (5-HT transporter) and an antagonist of the 5-HT1B and 5-HT1D receptors. This compound significantly increases extracellular serotonin levels in the frontal cortex of mouse models. LY393558 is valuable for research focused on depression and related serotonin modulation studies.
Product Information
Catalog NumA46017
FormulaC26H31FN4O4S2
Molecular Weight546.68
CAS Number271780-64-4
SMILESO=S(C1=CC=C(N(CCN2CC=C(C3=CNC4=C3C=CC(F)=C4)CC2)S(N(C(C)C)C5)(=O)=O)C5=C1)(C)=O
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