LY487379 is a selective positive allosteric modulator (PAM) of the human metabotropic glutamate receptor 2 (mGluR2). It enhances glutamate-stimulated [35S]GTPγS binding with an EC50 of 1.7 μM for mGluR2 and >10 μM for mGluR3. LY487379 has been demonstrated to promote cognitive flexibility and facilitate behavioral inhibition in rat models, making it a valuable tool for schizophrenia research and the exploration of neuropsychological mechanisms.
LY487379 is a selective positive allosteric modulator (PAM) of the human metabotropic glutamate receptor 2 (mGluR2). It enhances glutamate-stimulated [35S]GTPγS binding with an EC50 of 1.7 μM for mGluR2 and >10 μM for mGluR3. LY487379 has been demonstrated to promote cognitive flexibility and facilitate behavioral inhibition in rat models, making it a valuable tool for schizophrenia research and the exploration of neuropsychological mechanisms.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
