LysoFP-NO2

Catalog No.: B11087
Fluorescent Dye
LysoFP-NO2 is a turn-on fluorescent probe specifically designed for the detection of carbon monoxide (CO) in lysosomal compartments. Upon interaction with lysosomal CO, LysoFP-NO2 is converted to the highly fluorescent LysoFP-NH2, enabling enhanced detection capabilities. This probe exhibits remarkable selectivity for CO, distinguishing it from various reactive nitrogen, oxygen, and sulfur species. It has excitation and emission maxima at 440 nm and 528 nm, respectively, and demonstrates low cytotoxicity in HepG2 cells at a concentration of 30 μM for up to five hours, making it suitable for various cellular imaging applications.
Grouped product items
Size Price Stock Qty
1mg
$65.00
In stock
5mg
$175.00
In stock
10mg
$335.00
In stock
25mg
$770.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionLysoFP-NO2 is a turn-on fluorescent probe specifically designed for the detection of carbon monoxide (CO) in lysosomal compartments. Upon interaction with lysosomal CO, LysoFP-NO2 is converted to the highly fluorescent LysoFP-NH2, enabling enhanced detection capabilities. This probe exhibits remarkable selectivity for CO, distinguishing it from various reactive nitrogen, oxygen, and sulfur species. It has excitation and emission maxima at 440 nm and 528 nm, respectively, and demonstrates low cytotoxicity in HepG2 cells at a concentration of 30 μM for up to five hours, making it suitable for various cellular imaging applications.
Product Information
Catalog NumB11087
FormulaC18H17N3O5
Molecular Weight355.34
CAS Number69408-75-9
SMILESO=C1N(CCN2CCOCC2)C(C3=CC([N+]([O-])=O)=CC4=CC=CC1=C34)=O
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