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(M)-AVI-4773

Coronaviruses MPro Inhibitor

(M)-AVI-4773 is a potent inhibitor of coronavirus main protease (MPro), specifically targeting the enzyme with an IC50 of 2.5 nM against SARS-CoV-2 MPro. This orally active compound is capable of crossing the blood-brain barrier and demonstrates a rapid antiviral effect in mouse models of MERS-CoV and SARS-CoV-2 infection. (M)-AVI-4773 is positioned as a valuable tool for research into antiviral therapies for coronavirus infections.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3111610-68-2
Applications	Coronaviruses MPro Inhibitor
Formula	C₂₃H₁₄F₂N₆O₂
Molecular Weight	444.39
SMILES	FC1=CC(N=N2)=C(C=C1F)N2C3=C(C)N(CC#C)C(N(C4=CN=CC5=C4C=CC=C5)C3=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.