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M-H2S

H₂S Probe

M-H2S is an endoplasmic reticulum-targeted near-infrared fluorescent probe designed for the selective detection of hydrogen sulfide (H₂S) in living cells and zebrafish. With a detection limit of 39.1 nM, M-H2S demonstrates a linear fluorescence intensity ratio response (F₆₅₀/F₅₆₀) over a concentration range of 0-40 μM, optimized for physiological pH conditions (7.2). This probe is particularly valuable for investigating the role of H₂S in endoplasmic reticulum functionality, cellular stress responses, and associated pathological conditions.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2522921-17-9
Applications	H₂S Probe
Formula	C₂₇H₂₂N₂O₃
Molecular Weight	422.48
SMILES	CC1(CC(/C=C/C2=CC=C(C=C2)OC(C3=CC=CC=C3C=O)=O)=C/C(C1)=C(C#N)\C#N)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.