Fig. 1 · Structure

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m-PEG-acid

PROTAC Linker

m-PEG-acid is a polyethylene glycol (PEG)-based linker designed for use in the development of PROTAC (Proteolysis Targeting Chimeras) molecules. Its primary mechanism facilitates the selective ubiquitination and degradation of target proteins. This compound is essential in the synthesis of novel PROTACs, enhancing chemical stability and solubility while improving their biological activity in research applications focused on targeted protein degradation.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 125220-94-2
Applications PROTAC Linker
Formula (C2H4O)nC4H8O3
SMILES
COCCOCCC(O)=O.[n]

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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