Fig. 1 · Structure

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m-PEG16-COOH

PROTAC Linkers

m-PEG16-COOH is a polyethylene glycol (PEG)-based linker designed for use in PROTAC (Proteolysis Targeting Chimeras) synthesis. This compound facilitates the conjugation of target proteins to E3 ubiquitin ligases, enabling the targeted degradation of specific proteins within cellular systems. It serves as a crucial component in the development of novel therapeutic agents aimed at modulating protein levels, making it valuable for research in cancer therapy and other diseases where protein degradation plays a key role.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 2933174-52-6
Applications PROTAC Linkers
Formula C34H68O18
Molecular Weight 764.89
SMILES
COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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