Fig. 1 · Structure
Documents & Downloads
m-PEG24-Mal
PROTAC Linkers
m-PEG24-Mal is a polyethylene glycol (PEG)-based linker designed for the synthesis of Protein Targeting Chimeras (PROTACs). This compound features a maleimide moiety that facilitates the conjugation of target proteins, enabling the effective degradation of specific proteins via the ubiquitin-proteasome pathway. Its application in the development of PROTACs supports research in targeted protein degradation and therapeutic strategies against various diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2579693-28-8 |
| Applications | PROTAC Linkers |
| Formula | C56H106N2O27 |
| Molecular Weight | 1239.44 |
| SMILES | COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCN1C(C=CC1=O)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.