Fig. 1 · Structure
Documents & Downloads
m-PEG3-OMs
PROTAC Linkers
m-PEG3-OMs is a polyethylene glycol (PEG)-based linker specifically designed for the construction of PROTACs (proteolysis-targeting chimeras). This compound facilitates the conjugation of E3 ligase-recruiting components to target proteins, enabling selective degradation through the ubiquitin-proteasome pathway. It is widely utilized in drug discovery and development research focused on targeted protein degradation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 74654-05-0 |
| Applications | PROTAC Linkers |
| Formula | C8H18O6S |
| Molecular Weight | 242.29 |
| SMILES | COCCOCCOCCOS(C)(=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.