Fig. 1 · Structure

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m-PEG3-S-PEG3-Boc

PROTAC Linkers

m-PEG3-S-PEG3-Boc is a PEG- and alkyl/ether-based PROTAC linker designed for use in the synthesis of proteolysis-targeting chimeras (PROTACs). This linker facilitates the effective conjugation of target proteins to E3 ligases, enhancing the specificity and efficacy of targeted protein degradation. It is suitable for various applications in chemical biology and drug discovery, enabling researchers to investigate the modulation of protein levels within cells.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 2055040-96-3
Applications PROTAC Linkers
Formula C20H40O8S
Molecular Weight 440.59
SMILES
COCCOCCOCCSCCOCCOCCOCCC(OC(C)(C)C)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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