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m-PEG3-Sulfone-PEG4-propargyl

PROTAC Linker

m-PEG3-Sulfone-PEG4-propargyl is a PEG-based linker specifically designed for the development of PROTACs (proteolysis targeting chimeras). This compound features an alkyne group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. m-PEG3-Sulfone-PEG4-propargyl serves as a versatile tool for researchers exploring targeted protein degradation and other chemical biology applications, enabling the precise assembly of bioconjugates and enhancing the efficacy of therapeutic interventions.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2055041-02-4
Applications	PROTAC Linker
Formula	C₁₈H₃₄O₉S
Molecular Weight	426.52
SMILES	COCCOCCOCCS(CCOCCOCCOCCOCC#C)(=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.