Fig. 1 · Structure
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m-PEG4-CH2-methyl ester
PROTAC Linkers
m-PEG4-CH2-methyl ester is a polyethylene glycol (PEG) and alkyl/ester-based PROTAC linker that serves as a crucial component in the synthesis of PROTAC molecules. This versatile linker enhances the solubility and pharmacokinetic properties of the resultant PROTACs. It is primarily utilized in drug discovery and development research, particularly for targeted protein degradation applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1920109-55-2 |
| Applications | PROTAC Linkers |
| Formula | C12H24O6 |
| Molecular Weight | 264.32 |
| SMILES | COCCOCCOCCOCCCC(OC)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.