Fig. 1 · Structure
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m-PEG4-phosphonic acid
PROTAC Linker
m-PEG4-phosphonic acid is a polyethylene glycol (PEG)-derived linker designed for use in the synthesis of PROTAC (proteolysis-targeting chimera) molecules. This compound facilitates the formation of stable linkages between target proteins and E3 ligases, enhancing the specificity and efficacy of protein degradation. Its application in PROTAC development makes it a valuable tool for researchers exploring targeted protein regulation and therapeutic interventions in various diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1872433-62-9 |
| Applications | PROTAC Linker |
| Formula | C9H21O7P |
| Molecular Weight | 272.23 |
| SMILES | COCCOCCOCCOCCP(O)(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.