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m-PEG6-C6-phosphonic acid ethyl ester

PROTAC Linkers

m-PEG6-C6-phosphonic acid ethyl ester is a PEG-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound facilitates the formation of bifunctional molecules that induce targeted protein degradation through the ubiquitin-proteasome pathway. Its unique structural properties enable efficient conjugation and enhanced solubility, making it suitable for advancing research in targeted therapeutic strategies and drug development.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2028281-88-9
Applications	PROTAC Linkers
Formula	C₂₃H₄₉O₉P
Molecular Weight	500.60
SMILES	COCCOCCOCCOCCOCCOCCCCCCCCP(OCC)(OCC)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.