m-PEG8-Tos

Catalog No.: A83687
PROTAC Linker
m-PEG8-Tos is a PEG-based PROTAC linker designed for the synthesis of Silymarin. It facilitates the formation of bifunctional molecules by linking target proteins to E3 ligases, enhancing targeted protein degradation. This compound serves as an essential tool in chemical biology research, particularly in studies focusing on targeted therapeutics and the modulation of protein levels within cellular systems.
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5mg
10mg
50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Descriptionm-PEG8-Tos is a PEG-based PROTAC linker designed for the synthesis of Silymarin. It facilitates the formation of bifunctional molecules by linking target proteins to E3 ligases, enhancing targeted protein degradation. This compound serves as an essential tool in chemical biology research, particularly in studies focusing on targeted therapeutics and the modulation of protein levels within cellular systems.
Product Information
Catalog NumA83687
FormulaC24H42O11S
Molecular Weight538.65
CAS Number82217-01-4
SMILESCOCCOCCOCCOCCOCCOCCOCCOCCOS(C1=CC=C(C)C=C1)(=O)=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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