Fig. 1 · Structure

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M4K2306

Cat. No. A84908 CAS 3034840-25-7

ALK2 Inhibitor

M4K2306 is a selective inhibitor of activin receptor-like kinase-2 (ALK2), exhibiting an IC50 of 7 nM. This compound demonstrates significant blood-brain permeability with a brain-to-plasma ratio of 75.6, making it a valuable tool for studying the role of ALK2 in neurological conditions. Its selective inhibition of ALK2 positions M4K2306 for research applications in understanding signaling pathways related to developmental processes and various diseases.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 3034840-25-7
Applications ALK2 Inhibitor
Formula C28H34N4O3
Molecular Weight 474.59
SMILES
CN1CC(C(C2=CC(OC)=C(C(OC)=C2)OC)=CN=C3)=C3C4=CC=C(N5CCN(CC5)C)C=C4C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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