M4K2306 is a selective inhibitor of activin receptor-like kinase-2 (ALK2), exhibiting an IC50 of 7 nM. This compound demonstrates significant blood-brain permeability with a brain-to-plasma ratio of 75.6, making it a valuable tool for studying the role of ALK2 in neurological conditions. Its selective inhibition of ALK2 positions M4K2306 for research applications in understanding signaling pathways related to developmental processes and various diseases.
M4K2306 is a selective inhibitor of activin receptor-like kinase-2 (ALK2), exhibiting an IC50 of 7 nM. This compound demonstrates significant blood-brain permeability with a brain-to-plasma ratio of 75.6, making it a valuable tool for studying the role of ALK2 in neurological conditions. Its selective inhibition of ALK2 positions M4K2306 for research applications in understanding signaling pathways related to developmental processes and various diseases.
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