Fig. 1 · Structure

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M4K2308

Cat. No. A84900 CAS 3034840-18-8

ALK2 Inhibitor

M4K2308 is a selective inhibitor of ALK2, featuring an IC50 of 2 nM. This compound demonstrates remarkable selectivity for ALK2 compared to ALK5, with an IC50 of 224 nM. M4K2308 is valuable for research applications focused on diffuse intrinsic pontine glioma (DIPG), allowing for deeper understanding of this challenging neuro-oncological condition.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 3034840-18-8
Applications ALK2 Inhibitor
Formula C26H29N3O4
Molecular Weight 447.53
SMILES
COC(C=C1C2=C3C(C4=CC=C(N5CCNCC5)C=C4OCC3)=CN=C2)=C(C(OC)=C1)OC

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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