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M918

Catalog No.: A90692
Cell Penetrating Peptide
M918 is a cell-penetrating peptide that facilitates internalization by cells through endocytosis. Demonstrating effective penetration of a wide range of cell types without inducing toxicity, M918 is a valuable tool for advancing gene therapy and drug delivery system research. Its ability to traverse cellular membranes enhances its potential applications in therapeutic development and cellular studies.
M918 955937-87-8 Cell Penetrating Peptide
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Research use only. We do not sell to patients.
Data Sheet SDS Compound Handling Instructions

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionM918 is a cell-penetrating peptide that facilitates internalization by cells through endocytosis. Demonstrating effective penetration of a wide range of cell types without inducing toxicity, M918 is a valuable tool for advancing gene therapy and drug delivery system research. Its ability to traverse cellular membranes enhances its potential applications in therapeutic development and cellular studies.
Product Information
Catalog NumA90692
FormulaC116H208N44O23S2
Molecular Weight2651.30
CAS Number955937-87-8
SequenceMet-Val-Thr-Val-Leu-Phe-Arg-Arg-Leu-Arg-Ile-Arg-Arg-Ala-Cys-Gly-Pro-Pro-Arg-Val-Arg-Val-NH2
Sequence shorteningMVTVLFRRLRIRRACGPPRVRV-NH2
SMILESC(=O)(N1[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](C(C)C)C(N)=O)=O)CCCNC(=N)N)=O)C(C)C)=O)CCCNC(=N)N)=O)CCC1)[C@H]2N(C(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC3=CC=CC=C3)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CCSC)N)=O)C(C)C)=O)[C@@H](C)O)=O)C(C)C)=O)CC(C)C)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CC(C)C)=O)CCCNC(=N)N)=O)[C@H](CC)C)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)C)=O)CS)=O)=O)CCC2
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