Documents & Downloads

MAGL-IN-14

MAGL Inhibitor

MAGL-IN-14 is a potent inhibitor of monoacylglycerol lipase (MAGL), exhibiting an IC50 of 0.00289 μM in HEK293 cells and 0.002 μM in PC3 cells. This compound demonstrates significant potential for regulating endocannabinoid signaling by inhibiting lipid metabolism. MAGL-IN-14 is suitable for applications in cannabinoid research, metabolic studies, and the investigation of neurological disorders associated with altered endocannabinoid levels.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2770967-04-7
Applications	MAGL Inhibitor
Formula	C₁₇H₁₇F₆N₃O₃
Molecular Weight	425.33
SMILES	O=C([C@H]1CC12CCN(C(OC(C(F)(F)F)C(F)(F)F)=O)CC2)NC3=CC=CN=C3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.