Fig. 1 · Structure
Documents & Downloads
MAGL-IN-18
MAGL Inhibitor
MAGL-IN-18 is a highly potent inhibitor of Monoacylglycerol lipase (MAGL), demonstrating an IC50 value of 0.03 nM. By selectively inhibiting MAGL, this compound plays a crucial role in modulating endocannabinoid signaling, making it valuable for research into pain, inflammation, and neurodegenerative diseases. MAGL-IN-18 can be utilized in studies focused on the therapeutic potential of endocannabinoids and their role in various biological processes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 3036792-74-9 |
| Applications | MAGL Inhibitor |
| Formula | C23H28F3N7O |
| Molecular Weight | 475.51 |
| SMILES | O=C(N1CC2(CC(N3C=NC(C4CC4)=N3)C2)C1)N(C5)CC65CC(CC7=C(C(F)(F)F)NN=C7)C6 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.