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MAGL-IN-8

MAGL Inhibitor

MAGL-IN-8 is a reversible inhibitor of monoacylglycerol lipase (MAGL), exhibiting an IC50 value of 2.5 ± 0.4 nM for human MAGL. This compound serves as a valuable tool for studying the role of MAGL in the regulation of endocannabinoid metabolism and related signaling pathways. Its precise inhibition of MAGL makes MAGL-IN-8 suitable for research applications focused on neurobiology, pain, and inflammation.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3017151-71-9
Applications	MAGL Inhibitor
Formula	C₂₅H₂₃F₃N₂O₂S
Molecular Weight	472.52
SMILES	O=C(C1=CC=CC(O)=C1)N2CCC(CC3=CC=CC(SC4=NC=CC(C(F)(F)F)=C4)=C3)CC2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.