Mal-Ala-Ala-PAB-PNP

Catalog No.: A43321
ADC Linker
Mal-Ala-Ala-PAB-PNP is a cleavable linker designed for use in the development of antibody-drug conjugates (ADCs). This compound is engineered to facilitate the selective release of therapeutic agents upon internalization by target cells, enhancing the efficacy of targeted cancer therapies. Its application in ADC synthesis supports the study of targeted delivery mechanisms and the optimization of therapeutic strategies in oncology research.
Grouped product items
Size Price Stock Qty
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

Loading distributor info...

Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMal-Ala-Ala-PAB-PNP is a cleavable linker designed for use in the development of antibody-drug conjugates (ADCs). This compound is engineered to facilitate the selective release of therapeutic agents upon internalization by target cells, enhancing the efficacy of targeted cancer therapies. Its application in ADC synthesis supports the study of targeted delivery mechanisms and the optimization of therapeutic strategies in oncology research.
Product Information
Catalog NumA43321
FormulaC30H33N5O10
Molecular Weight623.61
CAS Number2003260-14-6
SMILESO=C(C=CC1=O)N1CCCCCC(N[C@@H](C)C(N[C@@H](C)C(NC2=CC=C(C=C2)COC(OC3=CC=C(C=C3)[N+]([O-])=O)=O)=O)=O)=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2