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Mal-amido-PEG2-Val-Cit-PAB-PNP

Catalog No.: A42808
ADC linker
Mal-amido-PEG2-Val-Cit-PAB-PNP is a cleavable 2 unit polyethylene glycol (PEG) linker designed for use in antibody-drug conjugate (ADC) synthesis. This linker facilitates the selective release of cytotoxic agents upon internalization of the ADC by target cells, enhancing therapeutic efficacy. Its unique structural features support various research applications in the development of targeted cancer therapies.
Mal-amido-PEG2-Val-Cit-PAB-PNP 2112738-13-1 ADC linker
Grouped product items
Size Price Stock Qty
2mg
$90.00
In stock
25mg
$285.00
In stock
50mg
$445.00
In stock
100mg
$710.00
In stock
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMal-amido-PEG2-Val-Cit-PAB-PNP is a cleavable 2 unit polyethylene glycol (PEG) linker designed for use in antibody-drug conjugate (ADC) synthesis. This linker facilitates the selective release of cytotoxic agents upon internalization of the ADC by target cells, enhancing therapeutic efficacy. Its unique structural features support various research applications in the development of targeted cancer therapies.
Product Information
Catalog NumA42808
FormulaC39H50N8O14
Molecular Weight854.86
CAS Number2112738-13-1
SMILESO=C(NC1=CC=C(COC(OC2=CC=C(N(=O)=O)C=C2)=O)C=C1)[C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCOCCOCCNC(CCN(C3=O)C(C=C3)=O)=O)=O)=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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Antibody-drug Conjugates (ADC) > ADC Linker