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Mal-amido-PEG9-Val-Ala-PAB-SG3200

Catalog No.: A43253
ADC Linker
Mal-amido-PEG9-Val-Ala-PAB-SG3200 is a cleavable linker designed for use in antibody-drug conjugates (ADCs). Its structural features enable selective release of therapeutic agents upon cleavage, enhancing targeted drug delivery. This linker is crucial for research applications focusing on the development and optimization of ADC formulations.
Mal-amido-PEG9-Val-Ala-PAB-SG3200 1817788-75-2 ADC Linker
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMal-amido-PEG9-Val-Ala-PAB-SG3200 is a cleavable linker designed for use in antibody-drug conjugates (ADCs). Its structural features enable selective release of therapeutic agents upon cleavage, enhancing targeted drug delivery. This linker is crucial for research applications focusing on the development and optimization of ADC formulations.
Product Information
Catalog NumA43253
FormulaC75H101N9O24
Molecular Weight1512.65
CAS Number1817788-75-2
SMILESO=C(C=CC1=O)N1CCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(N[C@@H](C(C)C)C(N[C@@H](C)C(NC(C=C2)=CC=C2COC(N3C4=CC(OCCCOC5=C(C=C6C(N=C[C@@]7([H])N(C=C(C7)C)C6=O)=C5)OC)=C(OC)C=C4C(N8[C@](CC(C)=C8)([H])[C@@H]3O)=O)=O)=O)=O)=O)=O
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Antibody-drug Conjugates (ADC) > ADC Linker