Fig. 1 · Structure

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Mal-PEG2-NH-Boc

PROTAC Linkers

Mal-PEG2-NH-Boc is a polyethylene glycol (PEG) based linker designed for use in the synthesis of PROTAC (proteolysis-targeting chimera) compounds. This linker facilitates the conjugation of target proteins to E3 ligases, enabling the selective degradation of proteins of interest. Mal-PEG2-NH-Boc is essential for developing advanced biopharmaceuticals in targeted protein degradation research.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 660843-21-0
Applications PROTAC Linkers
Formula C15H24N2O6
Molecular Weight 328.36
SMILES
O=C(OC(C)(C)C)NCCOCCOCCN1C(C=CC1=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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