Biological Activity
Mal-PEG2-VCP-Eribulin consists the ADCs linker (Mal-PEG2-VCP) and Eribulin. Eribulin is a mechanistically unique microtubule inhibitor for cancer. Mal-PEG2-VCP-Eribulin is an Eribulin-based drug for antibody conjugates.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 7.28 mL | 36.38 mL | 72.75 mL |
0.5 mM | 1.46 mL | 7.28 mL | 14.55 mL |
1 mM | 0.73 mL | 3.64 mL | 7.28 mL |
5 mM | 0.15 mL | 0.73 mL | 1.46 mL |
*The above data is based on the productmolecular weight 1374.57. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A18555 |
---|---|
Actions | Inhibitor |
M. Wt | 1374.57 |
Formula | C70H99N7O21 |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 2130869-18-8 |
SMILES | C=C1C[[email protected]@]2([H])O[[email protected]@]1([H])CC[[email protected]]3([H])O[[email protected]](C([[email protected]](C)C3)=C)([H])C[[email protected]@]4([H])[[email protected]]([[email protected]@H](OC)[[email protected]@H](C[[email protected]](O)CNC(OCC5=CC=C(NC([[email protected]](CCCNC(N)=O)NC([[email protected]](C(C)C)NC(CCOCCOCCN6C(C=CC6=O)=O)=O)=O)=O)C=C5)=O)O4)([H])CC(C[[email protected]]7([H])O[[email protected]]8([H])[[email protected]]9([H])O[[email protected]@]%10(O[[email protected]@]%11([H])[[email protected]@](O[[email protected]]9([H])[[email protected]@]%11([H])O[[email protected]@]8([H])CC7)([H])C%10)CC2)=O |
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