Mal-PEG3-VCP-NB is a degradable antibody-drug conjugate (ADC) linker characterized by its maleimide functional group, a three-unit polyethylene glycol (PEG) spacer, and a valine-citrulline (VCP) cleavage site. This compound facilitates site-specific conjugation to antibodies, enhancing the therapeutic efficacy of ADCs while allowing for controlled release of cytotoxic agents. It is primarily utilized in the development of ADCs for targeted cancer therapies.
Mal-PEG3-VCP-NB is a degradable antibody-drug conjugate (ADC) linker characterized by its maleimide functional group, a three-unit polyethylene glycol (PEG) spacer, and a valine-citrulline (VCP) cleavage site. This compound facilitates site-specific conjugation to antibodies, enhancing the therapeutic efficacy of ADCs while allowing for controlled release of cytotoxic agents. It is primarily utilized in the development of ADCs for targeted cancer therapies.
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